NACOGDOCHES — Lion Star is laying off upward of 50 people while closing its obstetrics unit, a women’s care clinic in Nacogdoches and a primary care clinic in Garrison, according to multiple people familiar with the decision.

Several employees were laid off Thursday, and staff at the Women’s Health Clinic in Nacogdoches and Care First Clinic in Garrison were told the locations would be permanently closed March 22. At least four physicians and two other midlevel providers will also be affected, according to people with knowledge of the layoffs.